Multi-Stream Collaboration

ImpactAlignment & leveraging create synergistic growth

ActionMaximize funding by coordinating cross-functional revenue generation

Key Performance Indicators

1

Value of proposed revenue by unit

Progress updates

2026: Q1-Q2

Addressed 2026 deviance from forecast re: philanthropic and translational revenue streams with leadership and Board. Integrated quality control checkpoints into future budgeting for these streams. Underway now: calculating range of 2027 value by revenue stream and determining likely estimation.

2

Value of secured revenue by unit

Progress updates

2026: Q1-Q2$4.535M

Government: $3,088M Foundation: $816k Industry/Other: $306k Licensing/IP: $23k Gifts (restricted + unrestricted): $141k Other: $161k GRAND TOTAL: $4.535M

3

Percentage of funding opportunities involving more than one unit

Progress updates

2026: Q1-Q2

Underway: developing tracking mechanisms to support this KPI.

4

Time from opportunity identification to proposal submission

Progress updates

2026: Q1-Q2

Underway: developing tracking mechanisms to support this KPI.

Fundraising for the Future

ImpactOptimizing future funding ensures BTI sustainability

ActionIncrease philanthropic interest and support through strong cultivation, board activation, and strategic communication

Key Performance Indicators

1

$5M secured or pledged, with pipeline at 3× annual target (50% in 2028 and 100% by 2030) as part of the capital campaign.

Progress updates

2026: Q1-Q2

Scheduling the first meetings with the Campaign Steering Committee to identify prospects and build the pipeline.

2

Donor retention rate (from 60% by 2028 to 65% by 2030). Sector benchmark: 43.3%

Progress updates

2026: Q1-Q221%

We are currently at 21% of last year's donors retained. The majority of gifts were received during Q4, therefore this KPI will look very different when the year is closed.

3

Donor upgrade rate: existing donors who increase their gift year-over-year (10% by 2028, 20% by 2030). Sector benchmark: 8–12%

Progress updates

2027: Q1-Q29%

Most of our individual gifts are made during Q4. This KPI will change by the end of the year.

4

# of new funders introduced by board members per year (target: 5 qualified introductions per year by 2028, 14 by 2030)

Progress updates

2026: Q1-Q23

Rockefeller Foundation, Bezos Earth Fund, and Gates Foundation contacts facilitated by board members. Simons Foundation contact is currently ongoing.

Revenue Visibility and Forecasting

ImpactDynamic revenue expectations drive decision making

ActionIntegrate accurate forecasting across revenue types to improve current operations, transparency, and financial planning

Key Performance Indicators

1

% of revenue units (grants, IP and donations) with current, reconciled data in the integrated reporting system

Progress updates

2026: Q1-Q2100%

Q1 & Q2 actuals per stream reconciled to mid-year forecast. Underway now: adjustments to 2026 H2 expectations. Integration of verified data into financial system for future periods.

2

Forecast accuracy rate by revenue unit (target within ± 10% by 2030)

Progress updates

2026: Q1-Q2

Variance by Funding Type: actuals over/(actuals under) 6% Government 211% Foundation 181% Industry/Other Non-Traditional Revenue Streams: (74%) Licensing/IP (83%) Gifts (3%) Other

Acquisition, Retention, and Revenue Balance

ImpactCompetitive success & diversification protect BTI research

ActionProtect discovery and reduce revenue concentration by increasing funding renewals while improving new opportunity success rates

Key Performance Indicators

1

Minimum of 5 new active philanthropic accounts and 60–65% retention rate (60% by 2028, 65% by 2030)

Progress updates

2026: Q1-Q25

5 donors that were lapsed or are new made a donation during the first two quarters.

2

2 major gifts or funded projects from the Translational Office by 2030

Progress updates

2026: Q1-Q2200,000

$200,000 gift from Cane-Bridge Foundation to produce translational data that could support the foundation of a new pharma startup

3

No single revenue stream exceeds 80% of total revenue (by 2030), maintaining or increasing the existing streams

Progress updates

2026: Q1-Q2

Underway: developing tracking mechanisms to support this KPI.

4

No single funder exceeds 20% of total revenue (by 2030)

Progress updates

2026: Q1-Q2

Underway: developing tracking mechanisms to support this KPI.